Lymphocytosis (lim-foe-sie-TOE-sis), or a high lymphocyte count, is an increase in white blood cells called lymphocytes.

Lymphocytes help fight off diseases, so it's normal to see a temporary increase after an infection.A count significantly higher than 3,000 lymphocytes in a microliter of blood is generally considered to be lymphocytosis in adults.

Mayo Clinic offers appointments in Arizona, Florida and Minnesota and at Mayo Clinic Health System locations.Our general interest e-newsletter keeps you up to date on a wide variety of health topics.Lymphocytosis (lim-foe-sie-TOE-sis), or a high lymphocyte count, is an increase in white blood cells called lymphocytes. It can be as high as 9,000 lymphocytes per microliter. They are the main type of cell found in lymph, which prompted the name "lymphocyte". He is also a director at the Center for Vascular Biology Research and an assistant professor at Harvard Medical School.

Absolute Lymphocyte Count (ALC) Assesses number of lymphocytes and predicts CD4 count. The exact thresholds for lymphocytosis can vary slightly from one lab to another.Mayo Clinic does not endorse companies or products. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. IMPORTANT. Lymphocytes are a type of white blood cell, which is a cell that's an important part of your immune system. lymphocyte [lim´fo-sīt] any of the mononuclear nonphagocytic leukocytes found in the blood, lymph, and lymphoid tissues; they comprise the body's immunologically competent cells and their precursors. Lymphocytes are an important part of the immune system. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.© 1998-2020 Mayo Foundation for Medical Education and Research (MFMER). Enter your email address and we'll send you a link to reset your password.Creating an account is free, easy, and takes about 60 seconds.Frequently used in the ED setting because CD4 tests take longer to come back and need patient consent.Used in limited-resource settings where CD4 tests are costly or unavailable.Currently evidence is mostly around HIV-1 treatment-naive patients.Other viral infections such as influenza or EBV can cause lymphopenia.Nathan Shapiro, MD, is an attending physician in the Department of Emergency Medicine at Beth Israel Deaconess Medical Center.

Dr. Shapiro conducts translational and clinical research with a particular focus on endothelial cell dysfunction in sepsis.Assesses number of lymphocytes and predicts CD4 count.For research purposes only; answer does NOT impact results.MDCalc loves calculator creators – researchers who, through intelligent and often complex methods, discover tools that describe scientific facts that can then be applied in practice. These are real scientific discoveries about the nature of the human body, which can be invaluable to physicians taking care of patients.Subcategory of 'Diagnosis' designed to be very sensitiveDisease is diagnosed: prognosticate to guide treatmentServes as a surrogate for CD4 count in HIV patients who are naive to antiretroviral therapy in resource-limited areas. Your doctor might perform other tests to determine if your lymphocyte count is a cause for concern.

It usually occurs after an illness and is harmless and temporary. They help fight off diseases, so it's normal to see a temporary rise in the number of lymphocytes after an infection. A lymphocyte is one of the subtypes of a white blood cell in a vertebrate's immune system. Tips for COVID-19: Use after diagnosis to determine dispo. A single copy of these materials may be reprinted for noncommercial personal use only.

Lymphopenia appears to be a predictor of COVID infection. Advertising revenue supports our not-for-profit mission.Check out these best-sellers and special offers on books and newsletters from Mayo Clinic.

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You can have a higher than normal lymphocyte count but have few, if any, symptoms. Lymphocytes include natural killer cells (which function in cell-mediated, cytotoxic innate immunity), T cells (for cell-mediated, cytotoxic adaptive immunity), and B cells (for humoral, antibody-driven adaptive immunity). We launched a COVID-19 Resource Center, including a critical review of recommended calcs. But it might represent something more serious, such as a blood cancer or a chronic infection.

In children, the threshold for lymphocytosis varies with age.

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