Borneol gel showed good pH value, conductivity, viscosity, spreadability, and stability before and after the 12 days in the freeze-thaw cycle. The preparation was left for about 15 min for attaining equilibrium while measuring. Centrifugation was performed with Model Centribio® 80-2B equipment.The spreadability of the BG5 was measured by spreading of 0.5 g of the gel on a circle of 2 cm diameter premarked on a glass plate and then a second glass plate was employed. Values are mean ± standard error.Center for Studies and Research of Medicinal Plants, Federal University of Vale do São Francisco, 56.304-205 Petrolina, PE, BrazilFederal University of Pernambuco, 50.670-901 Recife, PE, BrazilFederal University of Vale do São Francisco, 56.304-205 Petrolina, PE, BrazilDepartment of Physiology, Federal University of Sergipe, 49.100-000 São Cristóvão, SE, Brazil Borneol is a bicyclic monoterpenoid alcohol commonly used in traditional Chinese and Indian medicine. In this way, the glossiness of the product can be quantified by calculating the haze value after photo-curing.Figure 4 Color calculation results using [Color Evaluation – Color Diagnosis] programFor both color coats, the chromaticity value L* was increased by applying the matte top coat, so the appearance clearly became whiter. The clarity was determined by using the natural light and all the macroscopic analyses were realized comparing with carbopol.The BG5 was submitted to accelerated stability tests. However, this information can be obtained simultaneously using a JASCO spectrophotometer in a single measurement.Gel nails are a widely used cosmetic material because they are now cheaper and can be applied even at home. The current study was designed to develop a topical gel formulation containing the monoterpene borneol using carbopol as gel base and to evaluate its stability. Each test was done in triplicate with samples of 30 grams each.The BG5 sample was subjected to freeze and thaw cycle; the test was performed in 12 days with six cycles. In general, a top coat is applied over the color coat for various cosmetic purposes, such as to support decorations such as rhinestones, to make the gel nail last longer, or to create a texture such as gloss on the fingernail surface.In this study, to investigate gel nails with two different colors, samples with a single color and sample with a clear or matte top coat on a colored nail were prepared on a glass plate Figure 1. Dispersion obtained was neutralized with required quantity of triethanolamine to obtain pH 5.0 to 5.5. The borneol was successfully incorporated into the carbopol formulation. The analysis of pH and conductivity of formulation were done in triplicate and average values were calculated.The viscosity measurement of the borneol gel was performed with a Viscometer (Quimis® MOD 0860M21). Furthermore, this is considered an important factor in patient compliance with treatment.The consistency of the substance is one of the most important features to analgesic and anti-inflammatory topical formulations due to being applied to the thin layers of the skin, so that the gel viscosity plays an important role in controlling of drug permeation.
The glossiness and color of gel nail products are directly linked to their beauty, and the durability, quality and characteristics of gel nail materials can be numerically evaluated using JASCO instruments and software.Also see FTIR application note 030-AT-0258, which describes the photo-curing process for gel nails.1) Japanese patent publication No. Evaluation parameters of gel formulations are given in Table 2 and they are: pH The pH value of polyherbal gel formulation was determined by using a pH meter. At each speed, the corresponding dial reading was noted.The BG5 formulation was tested in triplicate, and each analysis was duplicated. The tests were performed eight months after the production of the formulation. In each cycle, the substance remained in a particular temperature for a period of 24 hours. However, further preclinical, clinical, and long-term stability studies should be required.The authors declare that they have no competing interests.Copyright © 2016 Milla Gabriela Belarmino Dantas et al.
The therapeutic efficacy of gels depends on their spread. Schematic diagram of gel nail on glass plateA color coat and a top coat, both with a thickness of about 0.1 mm, were applied to a glass plate, and cured using the manufacturer’s light source to prepare gel-nail samples with two different colors.JASCO has previously developed a method to calculate the haze value for reflected light based on that for transmitted light Figure 3 Schematic illustration of parameters used for reflection haze evaluationTo measure the scattered light, an integrating sphere was used to determine the reflection haze value by the following formula, and the glossiness of the sample was evaluated.The haze value is a numerical parameter related to the transparency of a sample and depends on characteristics such as surface roughness.
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