This feeling quickly ran into reality when I applied for a large number of faculty positions during my final year at Yale, and did not get a single interview. I said I would probably stop doing neutron scattering and go away on sabbatical to learn crystallography because that was how I could answer the really important questions in my field.

Their joining me was a stroke of luck and meant we would have a viable team at the LMB.With the decision to move to the LMB made, I decided to focus entirely on the 30S subunit. There were several reasons for this: it was the birthplace of crystallography and many technical developments had occurred there; it had a huge reputation in molecular biology; the director at the time, Aaron Klug, was considered a giant in the field of chromatin structure; finally, Vera and I were both anglophiles and we liked the idea of spending a year in England. Driving on the left side of the road after an overnight flight from New York was challenging. This was the beginning of a lifelong collaboration in their work. During that time, in addition to painting, she also became a children’s book writer and illustrator, and has published over 30 books.After my marriage at the age of 23, I was suddenly no longer alone but had a wife and a five-year-old stepdaughter, Tanya Kapka. As a longstanding research associate, she is the person who holds the lab together, training new people, making essential reagents, and becoming the general repository of knowledge for the lab. Once I had accepted that, I felt liberated and happier, but I have to confess that I felt some trepidation each October. One of the most useful collaborations was work on the nucleosome with Gerry Bunick, Ed Uberbacher and Don and Ada Olins. The canteen was especially wonderful for a sabbatical visitor because I quickly got to know lots of scientists. Even before coming to Utah, I had ideas of solving the structure of the ribosome, beginning with its small or 30S subunit.
At the lab, Kiyoshi Nagai, Daniela Rhodes, Phil Evans, and Andrew Leslie are among many people with whom I have become friends over the years.

History at your fingertips Richard Henderson, my director, suggested that I should accept more invitations to meetings and talks to get our story known if only to get proper recognition for our work, regardless of prizes.Deep down, I felt that the scientific event that transformed the field more than anything else was the determination of the atomic structures of the ribosomal subunits and the functional studies that followed as a result, to which we had made a major contribution. We were also helped by Malcolm Capel’s willingness to let us screen lots of our initial crystals at the NSLS at Brookhaven.

Ditlev used his computing skills to streamline our data collection and analysis procedures. However, international prizes for work on ribosomes always seemed to go to other people. The emotional support and stable home environment she provided has been invaluable to me and my work. I found that almost nobody there was working on routine problems just because they would lead to publishable results.
Venkatraman „Venki“ Ramakrishnan (* 1952 in Chidambaram, Tamil Nadu) ist ein indisch-britisch-amerikanischer Ribosomenforscher und Strukturbiologe. This reminded me of the story in I already knew that the LMB was a crowded laboratory with shakers and refrigerators in the hallways, but coming from Brookhaven, where my department building had originally been a bowling alley in an army base, this lack of poshness did not bother me. I made a friendly but wildly optimistic bet with him that we’d solve the entire 30S (including S7 of course) before he solved his complex.

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